Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus

5 Apr 2019

Abstract excerpt

Zika virus (ZIKV) infection is endemic to several world regions, and many others are at high risk for seasonal outbreaks. Synthetic DNA-encoded monoclonal antibody (DMAb) is an approach that enables in vivo delivery of highly potent mAbs to control infections. We engineered DMAb-ZK190, encoding the mAb ZK190 neutralizing antibody, which targets the ZIKV E protein DIII domain. In vivo-delivered DMAb-ZK190 achieved...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30962164
DOI: 10.1016/j.ymthe.2019.03.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika VirusPMID 30962164Read ↗

An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse modelSemantic proximity Read ↗

Integrated technology platform for accelerated discovery of antiviral antibody therapeuticsSemantic proximity Read ↗

Development of a Potent and Protective Germline-Like Antibody Lineage Against Zika Virus in a Convalescent Human.Semantic proximity Read ↗

Development of Zika Virus VaccinesSemantic proximity Read ↗

Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain IIISemantic proximity Read ↗

Recombinant Chimpanzee Adenovirus Vaccine AdC7-M/E Protects against Zika Virus Infection and Testis DamageSemantic proximity Read ↗

In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse ModelSemantic proximity Read ↗

Development of a potent and protective germline-like antibody lineage against Zika virus in a convalescent humanSemantic proximity Read ↗

A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetusesSemantic proximity Read ↗

In vivo delivery of synthetic DNA–encoded antibodies induces broad HIV-1–neutralizing activitySemantic proximity Read ↗

Development of a potent Zika virus vaccine using self-amplifying messenger RNASemantic proximity Read ↗

Zika virus vaccinesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.