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Article

APOE is a correlate of phenotypic heterogeneity in Alzheimer disease in a national cohort.

Neurology - 11 Feb 2020

Weintraub Sandra, Teylan Merilee, Rader Benjamin, Chan Kwun C G, Bollenbeck Mark, Kukull Walter A, Coventry Christina, Rogalski Emily, Bigio Eileen, Mesulam M-Marsel

Abstract excerpt

OBJECTIVE: To compare the proportion of APOE ε4 genotype carriers in aphasic vs amnestic variants of Alzheimer disease (AD). METHOD: The proportion of APOE ε4 carriers was compared among the following 3 groups: (1) 42 patients with primary progressive aphasia (PPA) and AD pathology (PPA/AD) enrolled in the Northwestern Alzheimer Disease Center Clinical Core; (2) 1,418 patients with autopsy-confirmed AD and...

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Identifiers

PMID: 31704790
DOI: 10.1212/WNL.0000000000008666
PMCID: PMC7136069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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