Article
Cognitive impairment in Alzheimer's disease is modified by APOE genotype.
Dementia and geriatric cognitive disorders - 1 Jan 2007
van der Vlies Annelies E, Pijnenburg Yolande A L, Koene Teddy, Klein Martin, Kok Astrid, Scheltens Philip, van der Flier Wiesje M
Abstract excerpt
AIM: We examined whether impairment in specific cognitive domains in Alzheimer's disease (AD) differed according to APOE genotype and age at onset. METHODS: Cognitive functions of 229 consecutive AD patients were assessed using Visual Association Test (VAT), Memory Impairment Screen+ (MIS+), VAT object naming, fluency test and Trail Making Test (TMT). Dementia severity was assessed using MMSE. ANOVAs were...
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