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Article

ApoE E4 is a susceptibility factor in amnestic but not aphasic dementias.

Alzheimer disease and associated disorders - 1 Jan 2000

Rogalski Emily Joy, Rademaker Alfred, Harrison Theresa M, Helenowski Irene, Johnson Nancy, Bigio Eileen, Mishra Manjari, Weintraub Sandra, Mesulam Marek-Marsel

Abstract excerpt

The goal of this study was to determine if the apolipoprotein ε gene, which is a well-established susceptibility factor for Alzheimer disease (AD) pathology in typical amnestic dementias, may also represent a risk factor in the language-based dementia, primary progressive aphasia (PPA). Apolipoprotein E genotyping was obtained from 149 patients with a clinical diagnosis of PPA, 330 cognitively healthy individuals...

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Source

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Identifiers

PMID: 21346518
DOI: 10.1097/WAD.0b013e318201f249
PMCID: PMC3100354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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