Article

Potential Metabolic Pathways Linking Alcohol Consumption to Osteoarthritis: A Mediation Analysis of Plasma Lipids

2026-06-29

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective:</bold> To investigate the causal relationship between alcohol consumption frequency and generalized osteoarthritis (OA) risk using Mendelian randomization (MR), and to quantify the potential mediating role of plasma lipids. <bold>Methods:</bold> A two-sample MR and two-step mediation analysis were performed using large-scale genome-wide association studies (GWAS)....

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Literature Corpus work: 400b76b1-bdc7-5028-9ca2-7b59c537ffae
DOI: 10.21203/rs.3.rs-10076368/v1

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