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Article

The effect of leptin on blood pressure considering smoking status: a Mendelian randomization study.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Apr 2020

Shen Luqi, Cordero José F, Wang Jia-Sheng, Shen Ye, Zhang Ruiyuan, Qi Yanling, Li Changwei

Abstract excerpt

Studies on leptin and blood pressure (BP) associations have yielded inconsistent findings. The current study aimed to evaluate the effect of genetically determined leptin on BP and to explore whether smoking status modified this effect. We conducted a Mendelian randomization analysis using the baseline data of 3860 participants in the Framingham Heart Study 3rd generation cohort. Pairwise associations among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31831886
DOI: 10.1038/s41440-019-0376-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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