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Article

Genetic predisposition to an adverse lipid profile limits the improvement in total cholesterol in response to weight loss.

Obesity (Silver Spring, Md.) - 1 Dec 2013

Walker Celia G, Holzapfel Christina, Loos Ruth J F, Mander Adrian P, Klopp Norman, Illig Thomas, Caterson Ian D, Hauner Hans, Jebb Susan A

Abstract excerpt

OBJECTIVE: Overweight and obesity are associated with a dyslipidaemia which can be improved by weight loss. Whether genetic predisposition to an adverse lipid profile modifies such beneficial effects of weight loss on lipid levels in overweight and obese individuals was examined. DESIGN AND METHODS: White European participants (n = 374) who completed a 12-month weight loss trial were genotyped for 36...

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Identifiers

PMID: 23418103
DOI: 10.1002/oby.20328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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