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Article

What drives the dynamics of HBV RNA during treatment?

19 Oct 2020

Abstract excerpt

Abstract Hepatitis B virus RNA (HBV RNA)–containing particles are encapsidated pre‐genomic RNA (pgRNA) detectable in chronically infected patients in addition to virions (HBV DNA) that have been suggested as a marker of the treatment efficacy. This makes promising the use of core protein allosteric modulators, such as RG7907, which disrupt the nucleocapsid assembly and profoundly reduce HBV RNA. Here, we...

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PMID: 33074571
DOI: 10.1111/jvh.13425

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