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Mathematical Models of Early Hepatitis B Virus Dynamics in Humanized Mice

9 Apr 2024

Abstract excerpt

Abstract Analyzing the impact of the adaptive immune response during acute hepatitis B virus (HBV) infection is essential for understanding disease progression and control. Here we developed mathematical models of HBV infection which either lack terms for adaptive immune responses, or assume adaptive immune responses in the form of cytolytic immune killing, non-cytolytic immune cure, or non-cytolytic-mediated...

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PMID: 38594319
DOI: 10.1007/s11538-024-01284-2

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