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Article

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways.

Nature neuroscience - 1 Feb 2015

Abstract excerpt

Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple genetic associations with such disorders, but better methods are needed to derive the underlying biological mechanisms that these signals indicate. We sought to identify biological pathways in GWAS data from over 60,000 participants from the Psychiatric Genomics Consortium. We developed an analysis framework to rank pathways...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25599223
DOI: 10.1038/nn.3922
PMCID: PMC4378867

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