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Article

Association between allelic variants in the glucagon-like peptide 1 and cholecystokinin receptor genes with gastric emptying and glucose tolerance.

Neurogastroenterology and motility - 1 Jan 2020

Anderson Bradley, Carlson Paula, Laurenti Marcello, Vella Adrian, Camilleri Michael, Desai Anshuman, Feuerhak Kelly, Bharucha Adil E

Abstract excerpt

BACKGROUND: Nutrient-mediated release of cholecystokinin and glucagon-like peptide-1 (GLP-1) regulates gastric emptying (GE) via duodenogastric feedback mechanisms; GLP-1 also regulates postprandial insulin secretion. Some patients with functional upper gastrointestinal symptoms have impaired glucose tolerance during enteral dextrose infusion. Our hypothesis was that variants in CCK, GLP-1, and TCF7L2...

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Share to Gastrointestinal Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Transcription Factor 7-Like 2 Protein

Source

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Identifiers

PMID: 31691451
DOI: 10.1111/nmo.13724
PMCID: PMC6923543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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