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Article

A preliminary candidate genotype-intermediate phenotype study of satiation and gastric motor function in obesity.

Obesity (Silver Spring, Md.) - 1 Jun 2010

Papathanasopoulos Athanasios, Camilleri Michael, Carlson Paula J, Vella Adrian, Nord Sara J Linker, Burton Duane D, Odunsi Suwebatu T, Zinsmeister Alan R

Abstract excerpt

Stomach motility contributes significantly to fullness sensation while eating and cessation of food intake in humans. Genes controlling adrenergic and serotonergic mechanisms (ADRA2A, GNB3, and SLC6A4) affect gastric emptying (GE), volume (GV), and satiation. Fat mass and obesity-associated gene (FTO) is linked with satiety. Our aim was to examine the association of these candidate genes with stomach functions...

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Source

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Identifiers

PMID: 19876010
DOI: 10.1038/oby.2009.360
PMCID: PMC2907132

Genes

GNB3
FTO
ADRB3

Provenance

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