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Article

Association of TCF7L2 allelic variations with gastric function, satiation, and GLP-1 levels.

Clinical and translational science - 1 Jun 2011

Vazquez-Roque Maria I, Camilleri Michael, Vella Adrian, Carlson Paula, Laugen Jeanette, Zinsmeister Alan R

Abstract excerpt

OBJECTIVE: Genetic variation in transcription factor 7-like 2 (TCF7L2), a regulator of proglucagon processing, is reproducibly associated with type 2 diabetes. GLP-1 alters gastric function and increases satiation. HYPOTHESIS: Genetic variation in TCF7L2 is associated with satiation, gastric motor function, and GLP-1 concentrations. METHODS: In 62 adults, a single nucleotide polymorphism (SNP) of TCF7L2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21707949
DOI: 10.1111/j.1752-8062.2011.00284.x
PMCID: PMC3125688

Genes

TCF7L2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Association of TCF7L2 allelic variations with gastric function, satiation, and GLP-1 levels.PMID 21707949Read ↗

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