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Article

Associations Between TCF7L2, PPARγ, and KCNJ11 Genotypes and Insulin Response to an Oral Glucose Tolerance Test: A Systematic Review.

Molecular nutrition & food research - 1 Feb 2025

Blanken Carmen P S, Bayer Sandra, Buchner Carro Sophie, Hauner Hans, Holzapfel Christina

Abstract excerpt

SCOPE: Insulin responses to standardized meals differ between individuals. This variability may in part be explained by genotype. This systematic review evaluates associations between genotype and insulin response to an oral glucose tolerance test (OGTT) in terms of insulin area under the curve (AUC). METHODS AND RESULTS: Three electronic databases (Web of Science, Embase, PubMed) were searched for studies...

Read the complete abstract on PubMed

Topics

Humans
Area Under Curve
Genotype
Glucose Tolerance Test
Insulin
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Postprandial Period

Potassium Channels, Inwardly Rectifying

PPAR gamma

Transcription Factor 7-Like 2 Protein

Kcnj11 Channel

Source

Open in PubMed Open full text

Identifiers

PMID: 39828593
DOI: 10.1002/mnfr.202400561
PMCID: PMC11791742

Genes

KCNJ11
TCF7L2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

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