Article
Effects of blood lead on coronary artery disease and its risk factors: a Mendelian Randomization study.
Scientific reports - 5 Nov 2019
Schooling C Mary, Johnson Glen D, Grassman Jean
Abstract excerpt
Lead is pervasive, although lead exposure has fallen in response to public health efforts. Observationally, lead is positively associated with cardiovascular disease and hypertension. We used separate-sample instrumental variable analysis with genetic instruments (Mendelian randomization) based on 13 single nucleotide polymorphisms (SNP), from a genome wide association study, strongly (p-value < 5 × 10-6) and...
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