Article
In-depth Mendelian randomization analysis of causal factors for coronary artery disease.
Scientific reports - 8 Jun 2020
Tan Yuan-De, Xiao Peng, Guda Chittibabu
Abstract excerpt
Selecting a set of valid genetic variants is critical for Mendelian randomization (MR) to correctly infer risk factors causing a disease. We here developed a method for selecting genetic variants as valid instrumental variables for inferring risk factors causing coronary artery disease (CAD). Using this method, we selected two sets of single-nucleotide-polymorphism (SNP) genetic variants (SNP338 and SNP363)...
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