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Article

Mendelian randomization studies in coronary artery disease.

European heart journal - 1 Aug 2014

Jansen Henning, Samani Nilesh J, Schunkert Heribert

Abstract excerpt

Epidemiological research over the last 50 years has discovered a plethora of biomarkers (including molecules, traits or other diseases) that associate with coronary artery disease (CAD) risk. Even the strongest association detected in such observational research precludes drawing conclusions about the causality underlying the relationship between biomarker and disease. Mendelian randomization (MR) studies can...

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Cholesterol Ester Transfer Proteins
Diabetes Complications
Fibrinogen
Genetic Pleiotropy
Lipoprotein(a)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phospholipases A2

Receptors, Interleukin-6

Serum Amyloid P-Component

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PMID: 24917639
DOI: 10.1093/eurheartj/ehu208

Genes

CAD

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