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Article

Unique characteristics of CpG island methylator phenotype (CIMP) in a Chinese population with colorectal cancer.

BMC gastroenterology - 5 Nov 2019

Liu Jiang, Tang Li, Yi Jinhua, Li Guimei, Lu Youwang, Xu Yu, Zhao Shuhua, Mao Rui, Li Xiaolu, Ren Li, Wang Kunhua

Abstract excerpt

BACKGROUND: Molecular characteristics of CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) have been well documented in Western, but not in Chinese, populations. METHODS: We investigated the incidence of CIMP, BRAF/KRAS mutation, and microsatellite instability (MSI) in a Chinese population with CRC (n = 401) and analysed associations between CIMP status and clinicopathological and molecular...

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Identifiers

PMID: 31690257
DOI: 10.1186/s12876-019-1086-x
PMCID: PMC6833289

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Source receipt: pubmed, retrieved 7 Sept 2026.

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