Article
Unique characteristics of CpG island methylator phenotype (CIMP) in a Chinese population with colorectal cancer.
BMC gastroenterology - 5 Nov 2019
Liu Jiang, Tang Li, Yi Jinhua, Li Guimei, Lu Youwang, Xu Yu, Zhao Shuhua, Mao Rui, Li Xiaolu, Ren Li, Wang Kunhua
Abstract excerpt
BACKGROUND: Molecular characteristics of CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) have been well documented in Western, but not in Chinese, populations. METHODS: We investigated the incidence of CIMP, BRAF/KRAS mutation, and microsatellite instability (MSI) in a Chinese p...
Topics
- Adult
- Aged
- Aged, 80 and over
- Asian People
- Colorectal Neoplasms
- CpG Islands
- DNA Methylation
- Female
- Humans
- Male
- Microsatellite Instability
- Middle Aged
- Mutation
- Phenotype
- Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins p21(ras)