Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The CpG island methylator phenotype in colorectal cancer: progress and problems.

Biochimica et biophysica acta - 1 Jan 2012

Hughes Laura A E, Khalid-de Bakker Carolina A J, Smits Kim M, van den Brandt Piet A, Jonkers Daisy, Ahuja Nita, Herman James G, Weijenberg Matty P, van Engeland Manon

Abstract excerpt

In recent years, attention has focused on the biology and potential clinical importance of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). While it is generally well accepted that etiologically and clinically distinct subgroups exist in this disease, a precise definition of CIMP remains to be established. Here, we summarize existing literature that documents the prevalence of CIMP in CRC,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to CpG Islands

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenetics and DNA Methylation

Share to Genetic factors in colorectal cancer

Share to Guidelines as Topic

Share to Pancreatic and Hepatic Oncology Research

Share to Phenotype

Source

Identifiers

PMID: 22056543
DOI: 10.1016/j.bbcan.2011.10.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The CpG island methylator phenotype in colorectal cancer: progress and problems.PMID 22056543Read ↗

Epigenetic alterations in colorectal cancer: the CpG island methylator phenotype.Semantic proximity Read ↗

Global differences in the prevalence of the CpG island methylator phenotype of colorectal cancerSemantic proximity Read ↗

CpG Island Methylator Phenotype-A Hope for the Future or a Road to Nowhere?Semantic proximity Read ↗

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.Semantic proximity Read ↗

The CpG island methylator phenotype in colorectal cancer.Semantic proximity Read ↗

Different definitions of CpG island methylator phenotype and outcomes of colorectal cancer: a systematic review.Semantic proximity Read ↗

Molecular phenotypes of colorectal cancer and potential clinical applicationsSemantic proximity Read ↗

Meta-analysis of the prognostic value of CpG island methylator phenotype in rectal cancer.Semantic proximity Read ↗

Colorectal cancer: epigenetic alterations and their clinical implications.Semantic proximity Read ↗

Unique characteristics of CpG island methylator phenotype (CIMP) in a Chinese population with colorectal cancer.Semantic proximity Read ↗

Methylator phenotype in colorectal cancer: A prognostic factor or not?Semantic proximity Read ↗

Biological significance of the CpG island methylator phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.