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Phenotypic Characterization of Chinese Rhesus Macaque Plasmablasts for Cloning Antigen-Specific Monoclonal Antibodies.

Frontiers in immunology - 1 Jan 2019

Zhang Fan, Wang Longyu, Niu Xuefeng, Li Jiashun, Luo Jia, Feng Yupeng, Yang Yanjia, He Ping, Fan Wenxia, Liang Renshan, Zheng Zhiqiang, Pan Weiqi, Li Chufang, Tan Yee Joo, Yu Haijian, Chen Ling, Li Pingchao

Abstract excerpt

Rhesus macaques (Macaca mulatta) are used as a human-relevant animal species for the evaluation of vaccines and as a source for cloning monoclonal antibodies (mAbs) that are highly similar to human-derived antibodies. Although antibody-secreting plasmablasts in humans are well-defined and can be easily isolated for mAb cloning, it remains unclear whether the same phenotypic markers could be applied for isolating...

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Identifiers

PMID: 31681312
DOI: 10.3389/fimmu.2019.02426
PMCID: PMC6798180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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