Article
Use of human leukocyte-specific monoclonal antibodies for clinically immunophenotyping lymphocytes of rhesus monkeys.
Cytometry - 1 Sept 1994
Reimann K A, Waite B C, Lee-Parritz D E, Lin W, Uchanska-Ziegler B, O'Connell M J, Letvin N L
Abstract excerpt
The rhesus monkey (Macaca mulatta) is an important experimental animal frequently utilized for studies of infectious diseases, immunity, hematopoiesis, and transplantation. Since the structure of cell surface molecules is phylogenetically conserved, monoclonal antibodies raised against human leukocyte antigens can sometimes recognize the homologous determinant on monkey leukocytes. To facilitate better...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, CD
- Blood Cells
- CD4-CD8 Ratio
- Genetic Variation
- HLA-D Antigens
- Humans
- Immunophenotyping
- Killer Cells, Natural
- Leukocytes