Article

Efficient methods for generation and expansion of, and gene delivery to Rhesus Macaque plasma B cells

2021-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Engineered long lived plasma cells have the potential to be a new area of cell therapy. A key step in developing this cell therapy is testing in a model with an intact immune system similar to humans. To that end, we have developed methods to purify, expand, and differentiate non-human primate (NHP; rhesus macaque ) B cells ex vivo . By comparing several media types and conditions, we consiste...

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Literature Corpus work: d8f0aef5-0df5-52f6-a56e-ccfca743a7e2
DOI: 10.1101/2021.09.30.462595

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