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Rhesus macaque antibody molecules: sequences and heterogeneity of alpha and gamma constant regions

15 Dec 2003

Abstract excerpt

Rhesus macaques (Macaca mulatta) are extensively used in vaccine development. Macaques infected with simian immunodeficiency viruses (SIV) or simian-human immunodeficiency viruses (SHIV) are the best animal model currently available for acquired-immune-deficiency-syndrome-related studies. Recent results emphasize the importance of antibody responses in controlling HIV and SIV infection. Despite the increasing...

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PMID: 14678200
DOI: 10.1111/j.1365-2567.2004.01767.x

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