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Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses

13 Dec 2016

Abstract excerpt

Antibodies raised in Indian rhesus macaques (Macaca mulatta, MM) in many preclinical vaccine studies are often evaluated in vitro for titer, antigen-recognition breadth, neutralization potency, and/or effector function, and in vivo for potential associations with protection. However, despite reliance on this key animal model in translation of promising candidate vaccines for evaluation in first in man studies,...

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PMID: 28018355
DOI: 10.3389/fimmu.2016.00589

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