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Article

Condemned or Not to Die? Gene Polymorphisms Associated With Cell Death in Pemphigus Foliaceus.

Frontiers in immunology - 1 Jan 2019

Bumiller-Bini Valéria, Cipolla Gabriel Adelman, Spadoni Mariana Basso, Augusto Danillo Gardenal, Petzl-Erler Maria Luiza, Beltrame Marcia Holsbach, Boldt Angelica Beate Winter

Abstract excerpt

Pemphigus foliaceus (PF) is an autoimmune blistering skin disease that occurs sporadically across the globe and is endemic in Brazil. Keratinocyte adhesion loss (acantholysis) is associated with high levels of anti-desmoglein 1 IgG autoantibodies, but the role of cell death is poorly understood in PF. Current evidence disqualifies apoptosis as the major cell death mechanism and no other process has yet been...

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Identifiers

PMID: 31681304
DOI: 10.3389/fimmu.2019.02416
PMCID: PMC6813369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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