Article
Polymorphisms within the tumor necrosis factor and lymphotoxin-alpha genes and endemic pemphigus foliaceus--are there any associations?
Tissue antigens - 1 Nov 2003
Roxo V M M S, Pereira N F, Pavoni D P, Lin M-T, Hansen J A, de O Poersch C, Filho A Marquart, Petzl-Erler M L
Abstract excerpt
The purpose of this study was to analyze the possible influence of the TNF and LTA loci polymorphisms on the susceptibility/resistance to endemic pemphigus foliaceus, also named fogo selvagem (FS), an autoimmune disease characterized by blisters due to acantholysis of the superficial-most epidermal cells. Autoantibodies, mainly of the IgG4 subclass, are directed against a desmosomal glycoprotein known as...
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