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Article

Pemphigus vulgaris and pemphigus foliaceus determined by CD86 and CTLA4 polymorphisms.

Clinics in dermatology - 1 Jan 2000

Tanasilovic Srdjan, Popadic Svetlana, Medenica Ljiljana, Popadic Dusan

Abstract excerpt

Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are rare autoimmune blistering diseases with presumed T-cell-dependent pathology. Activation of naïve T cells is dependent on antigen recognition, subsequent signaling through the T-cell receptor complex (signal 1), and various other interactions of T cells with antigen presenting cells that may be collectively designated as signal 2, which is unconditionally...

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Identifiers

PMID: 28274366
DOI: 10.1016/j.clindermatol.2016.05.021

Genes

CTLA4

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