Article
Involvement of the IL23/Th17 Pathway in the Pathogenesis of Tunisian Pemphigus Foliaceus.
Mediators of inflammation - 1 Jan 2018
Ben Jmaa M, Abida O, Fakhfakh R, Bahloul E, Sellami Kh, Gaddour L, Elloumi N, Ben Ayed M, Masmoudi A, Dhouib M, Abdelmoula M, Mahfoudh N, Makni H, Turki H, Masmoudi H
Abstract excerpt
Pemphigus foliaceus (PF) is a rare autoimmune skin disease caused by anti-Dsg1 pathogenic autoantibodies. It is considered as a Th2-mediated disease. Likewise, Th17 cells were recently described in the pathogenesis of the disease but their role is still unclear. We aimed to unravel the eventual implication of the IL23/Th17 pathway in the development of PF. A case-control study was conducted on 115 PF patients and...
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