Article
Investigation of the predisposing factor of pemphigus and its clinical subtype through a genome-wide association and next generation sequence analysis.
Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Feb 2019
Sun Y, Liu H, Yang B, Wang C, Foo J N, Bao F, Irwanto A, Yu G, Fu X, Wang Z, You J, Liu J, Zhou G, Liu J, Zhang F
Abstract excerpt
BACKGROUND: Pemphigus is an autoimmune blistering disease with pemphigus vulgaris (PV) and foliaceus (PF) as the two major histological subtypes. Associations with HLA molecules have been suggested, but specific HLA risk variants as well as non-HLA risk variants remain to be discovered. METHODS: We performed a two-stage genome-wide association study in the Chinese Han population through a genome-wide discovery...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.