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Article

Screening the full leucocyte receptor complex genomic region revealed associations with pemphigus that might be explained by gene regulation.

Immunology - 1 Jan 2019

Farias Ticiana Della Justina, Augusto Danillo G, de Almeida Rodrigo Coutinho, Malheiros Danielle, Petzl-Erler Maria Luiza

Abstract excerpt

Pemphigus foliaceus (PF) is a blistering autoimmune skin disease rare in most of the world but endemic in certain regions of Brazil. PF is characterized by the detachment of epidermal cells and the presence of autoantibodies against desmoglein 1. In previous studies, we have shown that genetic polymorphisms and variable expression levels of certain leucocyte receptor complex (LRC) genes were associated with PF....

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Identifiers

PMID: 30216441
DOI: 10.1111/imm.13003
PMCID: PMC6283660

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