Article
Genome-wide gene expression profiling reveals unsuspected molecular alterations in pemphigus foliaceus.
Immunology - 1 Nov 2014
Malheiros Danielle, Panepucci Rodrigo A, Roselino Ana M, Araújo Amélia G, Zago Marco A, Petzl-Erler Maria Luiza
Abstract excerpt
Pemphigus foliaceus (PF) is a complex autoimmune disease characterized by bullous skin lesions and the presence of antibodies against desmoglein 1. In this study we sought to contribute to a better understanding of the molecular processes in endemic PF, as the identification of factors that participate in the pathogenesis is a prerequisite for understanding its biological basis and may lead to novel therapeutic...
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