Article
GSK3β Polymorphisms Are Associated with Tumor Site and TNM Stage in Colorectal Cancer.
Archives of Iranian medicine - 1 Aug 2019
Rosales-Reynoso Mónica Alejandra, Zepeda-López Paulette, Saucedo-Sariñana Anilú Margarita, Pineda-Razo Tomas Daniel, Barros-Núñez Patricio, Gallegos-Arreola Martha Patricia, Flores-Martínez Silvia Esperanza, Sánchez-Corona José
Abstract excerpt
BACKGROUND: Mutations and polymorphisms of the GSK3β gene have been associated with several diseases including Alzheimer disease, diabetes and cancer; however, to date, no variants of this gene have been associated with colorectal cancer (CRC). This study aims to explore, for the first time, the association of the GSK3β rs334558 and rs6438552 polymorphisms with CRC. METHODS: Genomic DNA from 330 CRC patients and...
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