Article
Genetic variations are associated with lymph node metastasis in colorectal cancer patients.
Journal of surgical oncology - 1 Sept 2014
Lan Yuan-Tzu, Yang Shung-Haur, Lin Jen-Kou, Lin Chun-Chi, Wang Huann-Sheng, Chen Wei-Shone, Lin Tzu-Chen, Jiang Jeng-Kai, Chang Shih-Ching
Abstract excerpt
BACKGROUND AND OBJECTIVES: Regional lymph nodes (LNs) are believed to be a first-line barrier against tumor metastasis. However, it remains unclear whether underlying genetic factors exist and affect LN metastasis risk. We therefore evaluated inherited risk variants using single nucleotide polymorphisms (SNPs) in pathological T3 colorectal cancer patients in the absence or presence of LN metastasis. METHODS: The...
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