Article
Integrin alpha-2 and beta-3 gene polymorphisms and colorectal cancer risk.
International journal of colorectal disease - 1 Feb 2009
Gerger Armin, Hofmann Günter, Langsenlehner Uwe, Renner Wilfried, Weitzer Werner, Wehrschütz Martin, Wascher Thomas, Samonigg Hellmut, Krippl Peter
Abstract excerpt
BACKGROUND AND AIMS: Integrins such as alpha(2)beta(1), alpha(IIb)beta(3), and alpha(v)beta(3) have been suggested as key players for cancer development and progression. Several polymorphisms affecting these molecules, two in integrin alpha(2) (ITGA2 807C>T and 1648G>A) and one in beta(3) (ITGB3...
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