Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of GSK3β in breast cancer susceptibility.

Cancer biomarkers : section A of Disease markers - 1 Jan 2017

Aristizabal-Pachon Andrés Felipe, Castillo Willian Orlando

Abstract excerpt

BACKGROUND: Breast cancer is one of the principal causes of death among Brazilian women, so it is a challenge to find new and specific early diagnostic markers, using simple and fast procedures. GSK3β gene is an important Wnt signaling regulator involved in β-Catenin degradation. Wnt signaling is associated with initiation and progression process in many tumor types, and alterations in β-Catenin explain only a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Brazil

Share to Breast Neoplasms

Share to Glycogen Synthase Kinase 3 beta

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 27983530
DOI: 10.3233/CBM-160120
PMCID: PMC13020587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of GSK3β in breast cancer susceptibility.PMID 27983530Read ↗

The Landscape of Glycogen Synthase Kinase-3 Beta Genomic Alterations in Cancer.Semantic proximity Read ↗

Common Polymorphisms in the GSK3β Gene May Contribute to the Pathogenesis of Alzheimer Disease: A Meta-Analysis.Semantic proximity Read ↗

Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians.Semantic proximity Read ↗

Kinase-Inactive Glycogen Synthase Kinase 3β Promotes Wnt Signaling and Mammary TumorigenesisSemantic proximity Read ↗

Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progressionSemantic proximity Read ↗

GSK3β and cyclin D1 expression predicts outcome in early breast cancer patientsSemantic proximity Read ↗

The enzyme glycogen synthase kinase-3 is associated with specific forms of oncogenesis; what more do we need to know to achieve clinical benefit?Semantic proximity Read ↗

GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers.Semantic proximity Read ↗

DNMT1 rs2228611, rs2228612 and DNMT3A rs2276598, rs752208 Polymorphisms and Their Association with Breast Cancer Phenotype and Prognosis.Semantic proximity Read ↗

GSK3β Polymorphisms Are Associated with Tumor Site and TNM Stage in Colorectal Cancer.Semantic proximity Read ↗

Association analyses of a genetic variant in long non-coding RNA MEG3 with breast cancer susceptibility and serum MEG3 expression level in the Egyptian population.Semantic proximity Read ↗

TGF-β signaling pathway and breast cancer susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.