Article
A common gene variant in PLS3 predicts colon cancer recurrence in women.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2013
Szkandera Joanna, Winder Thomas, Stotz Michael, Weissmueller Melanie, Langsenlehner Tanja, Pichler Martin, Samonigg Hellmut, Renner Wilfried, Gerger Armin, Absenger Gudrun
Abstract excerpt
Recent evidence suggests that PLS3 (T-Plastin), an important member of the actin filamentous network, significantly influences cell invasion and metastasis. Germline polymorphisms within the PLS3 gene may impact the gene's function, resulting in inter-individual differences in tumor recurrence capacity. In the present study, we investigated the association of germline polymorphisms in PLS3 to predict time to...
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