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Article

Mendelian randomization analysis revealed potential causal factors for systemic lupus erythematosus.

Immunology - 1 Mar 2020

Mo Xingbo, Guo Yufan, Qian Qiyu, Fu Mengzhen, Lei Shufeng, Zhang Yonghong, Zhang Huan

Abstract excerpt

Genome-wide association studies (GWAS) have identified many loci for systemic lupus erythematosus (SLE). However, identification of functionally relevant genes remains a challenge. The aim of this study was to highlight potential causal genes for SLE in the GWAS loci. By applying Mendelian randomization (MR) methods, such as summary data-based MR (SMR), generalized SMR and MR pleiotropy residual sum and outlier,...

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Share to Cathepsin B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lupus Erythematosus, Systemic

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Source

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Identifiers

PMID: 31670388
DOI: 10.1111/imm.13144
PMCID: PMC7011638

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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