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Article

Association between mitochondria-related genes and systemic lupus erythematosus: Findings from Mendelian randomization study.

Medicine - 31 Oct 2025

Huang Xinglan, Deng Liehua, He Rongguo, Zhang Suiying, Deng Yuqiong, Zhao Xiaoqing, Wang Xingrong, Yang Yuqi, Zhang Ning, Cheng Xiping

Abstract excerpt

Systemic lupus erythematosus (SLE) is a severe autoimmune disease that damages various organs of the body. Mitochondrial dysfunction is closely related to the pathogenesis of SLE, but the genetic pathophysiological mechanism underlying this association has not been fully elucidated. The current study aims to elucidate the relationships between mitochondria-related genes and SLE via Mendelian randomization...

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Topics

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Share to DNA Methylation
Share to Genes, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Lupus Erythematosus, Systemic

Share to Mendelian Randomization Analysis

Share to Mitochondria

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 41261704
DOI: 10.1097/MD.0000000000045301
PMCID: PMC12582722

Genes

SPATA20
CASP9
MSRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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