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Article

Exploring the causality and pathogenesis of systemic lupus erythematosus in breast cancer based on Mendelian randomization and transcriptome data analyses.

Frontiers in immunology - 1 Jan 2022

Li Wenjie, Wang Rong, Wang Wei

Abstract excerpt

Introduction: There has been a cumulative interest in relationships between systemic lupus erythematosus (SLE) and cancer risk. Breast cancer is the most common cancer among women worldwide. However, the casual association and pathogenesis between SLE and breast cancer remains incompletely unknown. Methods: Mendelian randomization (MR) analysis was first conducted to investigate the potential causality between...

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Identifiers

PMID: 36726984
DOI: 10.3389/fimmu.2022.1029884
PMCID: PMC9885086

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