Article
Causal Effects of Gut Microbiome on Systemic Lupus Erythematosus: A Two-Sample Mendelian Randomization Study.
Frontiers in immunology - 1 Jan 2021
Xiang Kun, Wang Peng, Xu Zhiwei, Hu Yu-Qian, He Yi-Sheng, Chen Yue, Feng Ya-Ting, Yin Kang-Jia, Huang Ji-Xiang, Wang Jie, Wu Zheng-Dong, Yang Xiao-Ke, Wang De-Guang, Ye Dong-Qing, Pan Hai-Feng
Abstract excerpt
The observational association between gut microbiome and systemic lupus erythematosus (SLE) has been well documented. However, whether the association is causal remains unclear. The present study used publicly available genome-wide association study (GWAS) summary data to perform two-sample Mendelian randomization (MR), aiming to examine the causal links between gut microbiome and SLE. Two sets of MR analyses...
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