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Identifying the genetic association between systemic lupus erythematosus and the risk of autoimmune liver diseases.

Journal of autoimmunity - 1 May 2024

Huang Wei, Jin Tianyu, Zheng Wei, Yin Qiaoqiao, Yan Qiqi, Pan Hongying, Xu Chengan

Abstract excerpt

BACKGROUND: Previous studies on the relationship between systemic lupus erythematosus (SLE) and autoimmune liver diseases (AILDs) are inconclusive. Therefore, we employed Mendelian randomization (MR) to explore the causal associations between SLE and AILDs. METHODS: A two-sample MR analysis was performed using summary-level statistics sourced from genome-wide association study (GWAS) datasets. Inverse-variance...

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Autoimmune Diseases
Cholangitis, Sclerosing
Hepatitis, Autoimmune
Liver Cirrhosis, Biliary
Liver Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lupus Erythematosus, Systemic

Mendelian Randomization Analysis

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PMID: 38458076
DOI: 10.1016/j.jaut.2024.103188

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