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Systemic lupus erythematosus and epilepsy: A Mendelian randomization study.

Epilepsia open - 1 Dec 2024

Hu Yang, Lin Duo, Wu Dongmei, Zhang Yuqing, Li Gongbo

Abstract excerpt

OBJECTIVE: Numerous observational studies have found a relationship between systemic lupus erythematosus (SLE) and epilepsy; however, their causal relationship remains unclear. This study aimed to investigate the causal role of SLE in epilepsy or any of its subtypes using a two-sample Mendelian randomization (MR) analysis. METHODS: Single nucleotide polymorphisms (SNPs) linked to SLE were utilized as instrumental...

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Epilepsy
Genetic Predisposition to Disease
Genome-Wide Association Study
Lupus Erythematosus, Systemic
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39340433
DOI: 10.1002/epi4.13058
PMCID: PMC11633673

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