Article
Gene-gene interaction and association of Wnt/Β-catenin signalling pathway gene polymorphisms with ankylosing spondylitis susceptibility in the Chinese Han population.
Autoimmunity - 1 Jan 2000
Liu Rui, Zhang Xu, Jiang Guangming, Ma Yubo, Yang Jiajia, Wu Meng, Han Renfang, Chen Mengya, Yuan Yaping, Hu Xingxing, Pan Meijuan, Xu Shengqian, Xu Jianhua, Shuai Zongwen, Zou Yanfeng, Pan Guixia, Pan Faming
Abstract excerpt
Objectives: To explore the genetic interaction between Wnt/β-catenin signalling pathway genes and ankylosing spondylitis (AS) in the Chinese population.Methods: Six single-nucleotide polymorphisms (SNPs) in DKK1, LRP5, LRP6, and SOST genes were genotyped in 673 AS patients and 687 healthy controls by using SNPs can Technic. Single marker genetic association analysis was performed. Haplotypes were constructed...
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