Article
Association between vitamin D receptor gene polymorphism and ankylosing spondylitis in Han Chinese.
International journal of rheumatic diseases - 1 Oct 2017
Zhang Pingping, Li Qiuxia, Qi Jun, Lv Qing, Zheng Xuqi, Wu Xinyu, Gu Jieruo
Abstract excerpt
OBJECTIVES: To investigate whether vitamin D receptor (VDR) gene polymorphisms confer susceptibility to aankylosing spondylitis (AS) and study its polymorphisms in Han Chinese. METHODS: We screened single nucleotide polymorphisms (SNPs) in the VDR region through genome-wide genotyping chips in AS cases and healthy controls, then used the exome sequencing result to analyze all the potential AS-associated SNPs in...
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