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Article

Evaluation of WNT Signaling Pathway Gene Variants WNT7B rs6519955, SFRP4 rs17171229 and RSPO2 rs611744 in Patients with Dupuytren's Contracture.

Genes - 24 Aug 2021

Samulėnas Gediminas, Smalinskienė Alina, Rimdeika Rytis, Braziulis Kęstutis, Fomkinas Mantas, Paškevičius Rokas

Abstract excerpt

Dupuytren's contracture (DC) represents a chronic fibroproliferative pathology of the palmar aponeurosis, which leads to flexion contractures of finger joints and hand disability. In recent decades, the WNT signaling pathway has been revealed to play a significant role in the manifestation and pathogenesis of DC. Our study aimed to evaluate the associations between Dupuytren's contracture and WNT-related...

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Identifiers

PMID: 34573275
DOI: 10.3390/genes12091293
PMCID: PMC8469921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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