Article
High-order gene interactions between the genetic polymorphisms in Wnt and AhR pathway in modulating lung cancer susceptibility.
Personalized medicine - 1 Nov 2017
Bahl Charu, Singh Navneet, Behera Digambar, Sharma Siddharth
Abstract excerpt
AIM: Genetic variations present within Wnt and AhR pathway might be related to the lung cancer susceptibility. METHODS: A total of 555 subjects were genotyped using PCR-RFLP technique for polymorphic sites in DKK4, DKK3, DKK2, sFRP3, sFRP4, Axin2 and AhR. Multifactor dimensionality reduction method and classification and regression tree analysis was used. RESULTS: Overall sFRP4rs1802073 which has a cross...
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