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JAK-STAT signaling pathway-related gene single nucleotide polymorphisms and susceptibility to ankylosing spondylitis in eastern Chinese Han population.

Clinical rheumatology - 1 Feb 2023

Deng Yujie, Xu Wei, Gao Xing, Chen Yuting, Yang Hui, Shao Ming, Pan Faming

Abstract excerpt

OBJECTIVE: A case-control study was utilized to investigate the relationship between genetic variation of JAK-STAT signaling pathway-related genes and the susceptibility to ankylosing spondylitis (AS). METHODS: Fifteen SNPs in the JAK-STAT signaling pathway-related genes from 660 AS patients and 646 healthy controls were genotyped using iMLDR technology (JAK1: rs2230587, rs2230588, rs2780815, rs310241; JAK2:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Case-Control Studies
China
East Asian People
Genetic Predisposition to Disease
Genotype
Polymorphism, Single Nucleotide
Signal Transduction
Spondylitis, Ankylosing

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PMID: 36355252
DOI: 10.1007/s10067-022-06435-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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