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The Biological and Clinical Significance of Glutaminase in Luminal Breast Cancer

6 Aug 2021

Abstract excerpt

The glutamine metabolism has a key role in the regulation of uncontrolled tumour growth. This study aimed to evaluate the expression and prognostic significance of glutaminase in luminal breast cancer (BC). The glutaminase isoforms (GLS/GLS2) were assessed at genomic/transcriptomic levels, using METABRIC (n = 1398) and GeneMiner datasets (n = 4712), and protein using immunohistochemistry in well-characterised...

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PMID: 34439127
DOI: 10.3390/cancers13163963

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