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Glutamine Metabolism Regulators Associated with Cancer Development and the Tumor Microenvironment: A Pan-Cancer Multi-Omics Analysis.

Genes - 25 Aug 2021

Zou Jingwen, Du Kunpeng, Li Shaohua, Lu Lianghe, Mei Jie, Lin Wenping, Deng Min, Wei Wei, Guo Rongping

Abstract excerpt

BACKGROUND: In recent years, metabolic reprogramming has been identified as a hallmark of cancer. Accumulating evidence suggests that glutamine metabolism plays a crucial role in oncogenesis and the tumor microenvironment. In this study, we aimed to perform a systematic and comprehensive analysis of six key metabolic node genes involved in the dynamic regulation of glutamine metabolism (referred to as GLNM...

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Identifiers

PMID: 34573287
DOI: 10.3390/genes12091305
PMCID: PMC8466418

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