Article
Association of Genetic Polymorphisms of GREM1 Gene with Susceptibility to Non-Syndromic Cleft Lip with or without Cleft Palate in an Iranian Population.
Fetal and pediatric pathology - 1 Oct 2020
Rafighdoost Houshang, Poudineh Ali, Bahari Gholamreza, Ghaffari Hamidreza, Hashemi Mohammad
Abstract excerpt
Background: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is common congenital birth anomaly with multifactorial etiology. The GREM1 gene has been proposed to play a role in oral clefts development.Objective: The aim of the present study was to evaluate the correlation between GREM1 polymorphisms and the risk of NSCL/P in an Iranian population.Methods: Genotyping of rs7162202, rs12915554,...
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